Identification of six open reading frames in the Salmonella enterica subsp. enterica ser. Typhi viaB locus involved in Vi antigen production
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چکیده
منابع مشابه
Capsular Vi polysaccharide antigen in Salmonella enterica serovar typhi isolates.
Characterization of Salmonella enterica Serovar Typhi isolates for their Vi capsular polysaccharide antigen-related genetic sequences is desirable to define the role of isolates lacking such sequences in differential replication at unusual sites, including those coinfected with human immunodeficiency virus (HIV). Infection with Vi-negative strains might produce typhoid fever among those immuniz...
متن کاملThe Vi antigen of Salmonella typhi: molecular analysis of the viaB locus.
Strains of Salmonella typhi isolated from the blood of patients with typhoid fever invariably express a capsular polysaccharide, termed the Vi antigen. Vi antigen expression is controlled by two separate chromosomal loci, viaA and viaB. The viaA locus is commonly found in enteric bacteria. In contrast, the viaB locus appears to be specific to Vi-expressing strains of Salmonella and Citrobacter....
متن کاملMolecular differentiation between Salmonella enterica subsp enterica serovar Pullorum and Salmonella enterica subsp enterica serovar Gallinarum
S. Pullorum (SP) and S. Gallinarum (SG) are very similar. They are the agents of pullorum disease and fowl typhoid, respectively, and the two diseases are responsible for economic losses in poultry production. Although SP and SG are difficult to be differentiated in routine laboratory procedures, the ability to metabolize ornithine is a biochemical test that may be used to achieve this aim. Whi...
متن کاملMimotopes of the Vi antigen of Salmonella enterica serovar typhi identified from phage display peptide library.
The capsular polysaccharide Vi antigen (ViCPS) is an essential virulence factor and also a protective antigen of Salmonella enterica serovar Typhi. A random 12-mer phage-displayed peptide library was used to identify mimotopes (epitope analogues) of this antigen by panning against a ViCPS-specific monoclonal antibody (MAb) ATVi. Approximately 75% of the phage clones selected in the fourth round...
متن کاملDifferential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen
Salmonella enterica serovar Typhi expresses a capsule of Vi polysaccharide, while most Salmonella serovars, including S. Enteritidis and S. Typhimurium, do not. Both S. Typhi and S. Enteritidis express the lipopolysaccharide O:9 antigen, yet there is little evidence of cross-protection from anti-O:9 antibodies. Vaccines based on Vi polysaccharide have efficacy against typhoid fever, indicating ...
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ژورنال
عنوان ژورنال: Research in Microbiology
سال: 1993
ISSN: 0923-2508
DOI: 10.1016/0923-2508(93)90193-6